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MCP-1 Mouse anti-Human, Alexa Fluor 647, Clone: 5D3-F7, BD

Catalog No. BDB563496 Shop All BD Biosciences Products
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Catalog No. BDB563496 Supplier BD Biosciences Supplier No. 563496
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Description

Mouse Monoclonal Antibody

The 5D3-F7 monoclonal antibody specifically binds to human monocyte chemoattractant protein-1 (MCP-1), also known as CCL2 (C-C motif chemokine 2), Monocyte chemotactic and activating factor (MCAF), and Small-inducible cytokine A2 (SCYA2). MCP-1 is a 10-14 kDa glycoprotein member of the beta or CC family of chemokines. It expressed by monocytes, fibroblasts, endothelial cells and other cell types in response to IL-1, IL-6, TNF, and a variety of other stimuli. MCP-1 binds to and exerts its biological activity through G-protein coupled chemokine receptors including CCR2/CD192 and CCR4/CD194. It serves as a chemoattractant and activating factor for monocytes and other cell types including T cells, NK cells, and basophils.

TRUSTED_SUSTAINABILITY

Specifications

Antigen MCP-1
Applications Flow Cytometry
Classification Monoclonal
Clone 5D3-F7
Conjugate Alexa Fluor 647
Description CCL2; C-C motif chemokine 2; Chemokine (C-C motif) ligand 2; MCAF; SCYA2
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Recombinant Human MCP-1
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Cynomolgus, Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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