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MEK5 Mouse anti-Human, Clone: 1E5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519711

Catalog No. PIMA519711


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Description

Description

Peptide Sequence: MLWLALGPFP AMENQVLVIR IKIPNSGAVD WTVHSGPQLL FRDVLDVIGQ VLPEATTTAF EYEDEDGDRI TVRSDEEMKA MLSYYYSTVM EQQVNGQLIE PLQIFPRACK PPGERNIHGL

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Specifications

Specifications

MEK5
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q13163
Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MAP2K5; MEK5, MKK5, PRKMK5
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5607
ELISA, Immunocytochemistry, Immunofluorescence, Proximity Ligation Assay (PLA), Western Blot
1E5
Unconjugated
MAP2K5
Liquid
MAP2K5
MAP2K5 (AAH08838, 1 a.a. ∽ 120 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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