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METTL7A Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520636

Catalog No. PIPA520636


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Description

Description

A suggested positive control is MCF7 cell lysate. PA5-20636 can be used with blocking peptide PEP-0756.

MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
Specifications

Specifications

MettL7A
Polyclonal
Unconjugated
METTL7A
Liquid
METTL7A, METTL7A1
A 13 amino acid peptide near the center of human MettL7A.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9H8H3
PRO0066, AAM-B; methyltransferase-like protein 7A; protein AAM-B
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
25840, 70152
Documents
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