HLA-G Mouse anti-Human, Clone: G233, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119449
This antibody recognizes several isoforms of HLA-G expressed in all populations of extravillous trophoblast (cell columns, interstitial trophoblast, endovascular trophoblast, placental bed giant cells). It will not to cross-react with any other MHC Class I antigens (HLA-A, -B, -C, -E, -F).HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
|PBS with 15mM sodium azide; pH 7.4|
|4° C, do not freeze|
|ELISA, Flow Cytometry, Immunoprecipitation|
|Murine L cells transfected with both human beta-2 Microglobulin and HLA-G.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok