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MIP-1α Mouse anti-Human, APC, Clone: 11A3, BD

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Catalog No. BDB551533 Supplier BD Biosciences Supplier No. 551533
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Description

Mouse Monoclonal Antibody

The immunogen used to raise R139 was a CDw93 preparation as described. CDw93 is also known as C1q-binding protein. Human C1qRp is a 631 amino acid protein (∽66.5kD) protein that is highly expressed on monocytes/macrophages, neutrophil granulocytes but not on T and B lymphocytes. C1qRp binds C1q, the recognition subunit of the first component (C1) of the complement pathway, as well as MBL (Mannose-binding-lectin) and SPA(Pulmonary Surfactant Protein A). Human C1qRp is involved in the C1q-mediated enhancement of phagocytosis. R139 is suitable to detect C1qRp expression on cells of myeloid lineage by flow cytometry, C1qRp in cellular lysates by Western blotting or immunoprecipitation. In addition, R139 neutralizes C1qmediated enhancement of phagocytosis, as reported. CDw93 (C1qRp) has been reported to define a human stem cell population with hematopoietic and hepatic potential.

Host Species: Mouse
Clone: 11A3
Isotype: IgG2b κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen MIP-1α
Applications Flow Cytometry
Classification Monoclonal
Clone 11A3
Concentration 0.5mg/mL
Conjugate APC
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Cynomolgus, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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