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Description
Reacts with macrophage inflammatory protein-1α (MIP-1α), a member of the CC chemokine family of proteins. It is produced by T cells, B cells, Langerhans cells, neutrophils and macrophages. MIP-1α plays a role as an inhibitor of stem cell proliferation and as a chempattractant of B cells, eosinophils and cytotoxic T cells. Clone 11A3 also cross-reacts with an intracellular component of rhesus and cynomolgus macaque-LPS-stimulated peripheral blood monocytes. The reactivity pattern observed on CD14-positive cells is similar to that seen on normal human peripheral blood monocytes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody
development only or reported in the literature.
Host Species: Mouse
Clone: 11A3
Isotype: IgG2a κ
Species Reactivity: Human
Immunogen: Mouse IgG2a, κ
Intracellular Staining
Specifications
Specifications
| Antigen | MIP-1α |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 11A3 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | IgG2a, κ |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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