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MilliporeSigma™ anti-Mitoferrin-1/Mfrn1, Polyclonal

Catalog No. ABS1051MI Shop All MilliporeSigma Products
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Quantity:
100 μL
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
ABS1051MI 100 μL Unconjugated
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Catalog No. ABS1051MI Supplier MilliporeSigma™ Supplier No. ABS1051
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Description

Rabbit Polyclonal Antibody

Specifically detects Mitoferrin-1/Mfrn1 Clone: in Mouse samples, and it is validated for Western Blotting

Mitoferrin-1 (UniProt Q920G8; also known as mitochondrial iron transporter 1, mitochondrial solute carrier protein, solute carrier family 25 member 37) is encoded by the Slc25a37 (also known as Mfrn, Mfrn1, Mscp) gene (Gene ID 67712) in murine species. Mitoferrin-1 and mitoferrin-2 (Slc25a28, Mfrn2) mediate iron import into mitochondria. Mitoferrin-2 is expressed ubiquitously, whereas mitoferrin-1 is specifically induced in differentiating erythroid cells. Mfrn1 knockout in zebrafish and mice disrupts heme and [Fe-S] cluster synthesis as a result of a severe reduction in mitochondrial iron in erythroid progenitors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mitoferrin-1/Mfrn1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No. Q920G8
Gene Symbols Slc25a37, Mfrn, Mscp
Host Species Rabbit
Immunogen Linear peptide corresponding to the C-terminus of mouse Mitoferrin-1/Mfrn1.
Purification Method Unpurified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Signaling
Primary or Secondary Primary
Gene ID (Entrez) NP_080607
Test Specificity This antiserum does not react with spliced isofrms 2, 3, 4, and 5.
Target Species Mouse
Content And Storage −20°C for one year
Form Serum
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For Research Use Only

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