MilliporeSigma™ anti-Mitoferrin-1/Mfrn1, Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABS1051

Catalog No. ABS1051MI

Description

Specifically detects Mitoferrin-1/Mfrn1 Clone: in Mouse samples, and it is validated for Western Blotting

Mitoferrin-1 (UniProt Q920G8; also known as mitochondrial iron transporter 1, mitochondrial solute carrier protein, solute carrier family 25 member 37) is encoded by the Slc25a37 (also known as Mfrn, Mfrn1, Mscp) gene (Gene ID 67712) in murine species. Mitoferrin-1 and mitoferrin-2 (Slc25a28, Mfrn2) mediate iron import into mitochondria. Mitoferrin-2 is expressed ubiquitously, whereas mitoferrin-1 is specifically induced in differentiating erythroid cells. Mfrn1 knockout in zebrafish and mice disrupts heme and [Fe-S] cluster synthesis as a result of a severe reduction in mitochondrial iron in erythroid progenitors.

Specifications

• Antigen: Mitoferrin-1/Mfrn1
• Classification: Polyclonal
• Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
• Gene Symbols: Slc25a37, Mfrn, Mscp
• Immunogen: Linear peptide corresponding to the C-terminus of mouse Mitoferrin-1/Mfrn1.
• Quantity: 100 μL
• Research Discipline: Signaling
• Gene ID (Entrez): NP_080607
• Target Species: Mouse
• Form: Serum

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q920G8
• Host Species: Rabbit
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antiserum does not react with spliced isofrms 2, 3, 4, and 5.
• Content And Storage: −20°C for one year

For Research Use Only