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Description
Includes
Up to three rabbit IgG clones of 1mg each will be delivered to customer.
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq
Expression: Overexpression vector and transfection into 293H cell line
Order Info
- Customer may provide cell or tissue lysate for antibody screening.
- Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Specifications
Specifications
| Antigen | MLLT11 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Concentration | 1mg |
| Conjugate | Unconjugated |
| Description | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| Formulation | In 1X PBS, pH 7.4 |
| Gene | MLLT11 |
| Gene Accession No. | MLLT11 |
| Gene Alias | AF1Q, RP11-316M1.10 |
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