BRCA1 Antibody (17F8), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP141185

Catalog No. NBP141185

Description

BRCA1 Monoclonal specifically detects BRCA1 in Human, Mouse samples. It is validated for Western Blot, Chromatin Immunoprecipitation, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.

Specifications

• Antigen: BRCA1
• Classification: Monoclonal
• Concentration: 1.0mg/mL
• Dilution: Western Blot 1:500-1:3000, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 ug/ml, Immunoprecipitation, Immunohistochemistry-Paraffin, Chromatin Immunoprecipitation (ChIP) 1:10-1:500
• Gene Symbols: BRCA1
• Immunogen: Protein fragment expressed in E. coli corresponding to amino acids 762-1315.
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody does not recognize the delta exon 11 splice variant of BRCA1. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1

• Applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
• Clone: 17F8
• Conjugate: Unconjugated
• Gene Alias: BRCAI, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein, breast cancer 1, early onset, breast cancer type 1 susceptibility protein, EC 6.3.2, EC 6.3.2.-, IRIS, PNCA4, PSCP, subunit 1
• Host Species: Mouse
• Molecular Weight of Antigen: 220 kDa
• Quantity: 100 μL
• Research Discipline: Apoptosis, Breast Cancer, Cancer, Cell Biology, Chromatin Research, DNA Double Strand Break Repair, DNA Repair, Homologous Recombination, Tumor Suppressors, Ubiquitin Proteasome Pathway, Zinc Finger
• Gene ID (Entrez): 672
• Target Species: Human, Mouse
• Form: Purified

For Research Use Only