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Description
The RL73 monoclonal antibody specifically binds to mouse CD147. CD147 is type I membrane glycoprotein and member of the Ig superfamily. CD147 is also known as extracellular matrix metalloproteinase inducer (EMMPRIN) and gp42/basigin (BSG). The CD147 molecule is widely expressed on a variety of hemopoietic and non-hemopoietic cell types including thymocytes, lymphocytes, monocytes, granulocytes, erythroblasts and erythrocytes, endothelial cells and neoplasms. CD147 reportedly plays significant roles in the reproductive, nervous and immune systems and in tumor progression. In the immune system, CD147 can function as an adhesion molecule and signaling receptor that regulates leukocyte trafficking and immune and inflammatory responses.
Specifications
Specifications
| Antigen | CD147 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | RL73 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Description | Bsg; Basigin; BASI; EMMPRIN; gp 42; HT7; HT-7; Neurothelin |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse EL4 Cell Subline |
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