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CD282 Rat anti-Mouse, Alexa Fluor 647, Clone: 6C2, BD

Catalog No. BDB562625 Shop All BD Biosciences Products
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BDB562625 50 μg
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Catalog No. BDB562625 Supplier BD Biosciences Supplier No. 562625
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Description

Rat Monoclonal Antibody

The 6C2 monoclonal antibody specifically binds to the mouse Toll like receptor 2 (TLR2) that is also known as CD282. CD282 is a type 1 transmembrane glycoprotein and a TLR family member. It is expressed on the surface of monocytes, macrophages, dentritic cells, granulocytes, endothelial and epithelial cells. This pattern recognition receptor is important for sensing and transducing signals in response to microbial cell wall components including lipoproteins, peptidoglycans and lipoteichoic acid. CD282 signals through intracellular MYD88 and TRAF6 leading to NF-kappa-B activation and the production of cytokines and inflammatory mediators by responding cells. TLR2 plays a major role in mediating inflammatory and innate immune responses.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD282
Applications Flow Cytometry
Classification Monoclonal
Clone 6C2
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Description TLR2; Tlr2; Toll-like receptor 2; Ly105
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse TLR2 Transfected Cell Line
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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