Cytochrome b245 alpha Antibody (CS9), DyLight 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP140974UV

Catalog No. NBP140974UV

Description

Cytochrome b245 alpha Monoclonal specifically detects Cytochrome b245 alpha in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Frozen.

Specifications

• Antigen: Cytochrome b245 alpha
• Classification: Monoclonal
• Conjugate: DyLight 350
• Gene Accession No.: P13498
• Gene Symbols: CYBA
• Immunogen: Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
• Clone: CS9
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Frozen
• Gene Alias: cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
• Host Species: Mouse
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 1535
• Target Species: Human
• Form: Purified

For Research Use Only