Cytokeratin 14 Antibody (SPM263), PerCP, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234403PCP

Catalog No. NBP234403P

Description

Cytokeratin 14 Monoclonal specifically detects Cytokeratin 14 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Flow (Intracellular).

Specifications

• Antigen: Cytokeratin 14
• Classification: Monoclonal
• Conjugate: PerCP
• Gene Alias: CK14, CK-14, cytokeratin 14, cytokeratin-14, EBS3, EBS4, K14, keratin 14, keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner), keratin, type I cytoskeletal 14, Keratin-14, NFJ
• Host Species: Mouse
• Molecular Weight of Antigen: 50 kDa
• Quantity: 0.1 mL
• Research Discipline: Cytoskeleton Markers
• Gene ID (Entrez): 3861
• Target Species: Human, Mouse, Rat
• Form: Purified

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Clone: SPM263
• Dilution: Flow Cytometry, Flow (Intracellular)
• Gene Symbols: KRT14
• Immunogen: A synthetic peptide of 15 amino acid from the C-terminus of human Cytokeratin 14. (Uniprot: P02533)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG3 κ

For Research Use Only