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anti-Mouse Cytokeratin, Acidic (Type I or LMW), Alexa Fluor 488, Clone: SPM115, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234393AF488

Catalog No. NBP234393X


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Description

Description

Cytokeratin, Acidic (Type I or LMW) Monoclonal antibody specifically detects Cytokeratin, Acidic (Type I or LMW) in Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit, Reptile samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

Cytokeratin, Acidic (Type I or LMW)
SPM115
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Purified
Human epidermal keratin
49 kDa
0.1 ml
Store at 4C in the dark.
Monoclonal
Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit, Reptile
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Alexa Fluor 488
50mM Sodium Borate with 0.05% Sodium Azide
Mouse
IgG1 Kappa
Protein G purified
RUO
Primary
This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. MAb SPM116 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
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