Cytokeratin, Acidic (Type I or LMW) Antibody (SPM115), Alexa Fluor™ 488, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234393AF488

Catalog No. NBP234393X

Description

Cytokeratin, Acidic (Type I or LMW) Monoclonal specifically detects Cytokeratin, Acidic (Type I or LMW) in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit, Reptile samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cytokeratin, Acidic (Type I or LMW)
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Gene Alias: CK10, CK14, CK15, CK16, CK19, cytokeratin 10, cytokeratin 14, cytokeratin 15, cytokeratin 16, cytokeratin 19
• Immunogen: Human epidermal keratin (Uniprot: Q7Z794)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Test Specificity: This monoclonal antibody recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. monoclonal antibody SPM116 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

• Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: SPM115
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Host Species: Mouse
• Molecular Weight of Antigen: 49 kDa
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit, Reptile
• Form: Purified

For Research Use Only