anti-hCG Beta, DyLight 350, Clone: HCGb/54, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233110UV
DescriptionChorionic Gonadotropin beta Chain (hCG beta) Monoclonal antibody specifically detects Chorionic Gonadotropin beta Chain (hCG beta) in Human samples. It is validated for Western Blot, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
|Chorionic Gonadotropin beta Chain (HCG beta)|
|Western Blot, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|Chorionic Gonadotropin beta Antibody (HCGb/54)|
|Western Blot, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)|
|50mM Sodium Borate with 0.05% Sodium Azide|
|CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB|
|Protein A or G purified|
|Store at 4C in the dark.|
|This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.|
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