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IGF-I/IGF-1 Antibody (SPM406), HRP, Novus Biologicals™
SDP

Catalog No. NBP234409H Shop All R&D Systems Products
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Description

Mouse Monoclonal Antibody

IGF-I/IGF-1 Monoclonal specifically detects IGF-I/IGF-1 in Human, Mouse, Rat, Rabbit samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen IGF-I/IGF-1
Applications Western Blot, ELISA, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM406
Conjugate HRP
Dilution Western Blot, ELISA, Immunohistochemistry-Paraffin
Gene Alias IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C
Gene Symbols IGF1
Host Species Mouse
Immunogen Purified human IGF-I/IGF-1 protein (Uniprot: P05019)
Molecular Weight of Antigen 7.6 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cell Cycle and Replication
Primary or Secondary Primary
Gene ID (Entrez) 3479
Test Specificity This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Target Species Human, Mouse, Rat, Rabbit
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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