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MRP2 Antibody (M2III-6), Novus Biologicals™

Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP142349
Description
MRP2 Monoclonal specifically detects MRP2 in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.Specifications
MRP2 | |
Monoclonal | |
0.1 mg/ml | |
Western Blot 1:20-1:50, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:20-1:50, Immunohistochemistry-Paraffin 1:20, Immunohistochemistry-Frozen 1:20 | |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2, Canalicular multidrug resistance protein, canalicular multispecific organic anion transporter 1, CMOAT1, CMOATABC30, CMRP, DJS, KIAA1010, MRP2ATP-binding cassette sub-family C member 2, Multidrug resistance-associated protein 2 | |
Mouse | |
Protein G purified | |
RUO | |
Primary | |
M2III-6 reacts with an internal epitope of cMOAT/MRP2, a 170-180 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. cMOAT/MRP2 is closely related to the multidrug resistance related protein MRP, and cMOAT/MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2III-6 was raised against a bacterial fusion protein of cMOAB/MRP2, containing the 202-amino acid COOH terminal end of the protein. M2III-6 did not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products. | |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
IgG2a |
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
M2III-6 | |
Unconjugated | |
Q92887 | |
ABCC2 | |
The antibody reacts with the MRP2 antigen. | |
0.2 mL | |
ABC Transporters, Amino Acids Drugs and other small molecules, Cancer, Diabetes Research, Lipid and Metabolism | |
1244 | |
Human, Rat | |
Supernatant |
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