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NF-H Antibody (NF421), DyLight 488, Novus Biologicals™
SDP

Catalog No. NBP233102G Shop All R&D Systems Products
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NBP233102G 0.1 mL
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Catalog No. NBP233102G Supplier Novus Biologicals Supplier No. NBP233102G
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Description

Mouse Monoclonal Antibody

NF-H Monoclonal specifically detects NF-H in Human, Mouse, Rat, Porcine, Chicken samples. It is validated for Western Blot.

Specifications

Antigen NF-H
Applications ELISA
Classification Monoclonal
Clone NF421
Conjugate DyLight 488
Dilution ELISA
Gene Alias 200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Gene Symbols NEFH
Host Species Mouse
Immunogen Recombinant full-length human NF-H protein (Uniprot: P12036)
Molecular Weight of Antigen 200 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) 4744
Test Specificity This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Target Species Human, Mouse, Rat, Pig, Chicken
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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