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RORγt Mouse anti-Mouse, Unlabeled, Clone: Q31-378, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 562663
Description
The Q31-378 monoclonal antibody recognizes mouse RORgamma t (RORγt), an isoform of RORgamma (RORγ). RORγt is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. RORγt is expressed exclusively by lymphoid cells including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells, NKT cells and innate lymphoid cells such as lymphoid tissue inducer (LTi) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer’s patches.

Specifications
RORγt | |
Monoclonal | |
0.5mg/mL | |
RORγT; RORgt; RORgamma t; RORgammaT; Rorc2; Rorg; TOR; Thor; Nr1f3 | |
Mouse | |
Affinity Purified | |
RUO | |
Mouse | |
IgG2a κ |
Flow Cytometry | |
Q31-378 | |
Unconjugated | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Mouse RORγt Recombinant Protein | |
50 μg | |
Primary | |
Store undiluted at 4°C |
Safety and Handling
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