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MilliporeSigma™ anti-MSH2 Clone: FE11,

Catalog No. NA27100UG Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
NA27100UG 100 μg Unconjugated
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Catalog No. NA27100UG Supplier MilliporeSigma™ Supplier No. NA27100UG
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Description

Mouse Monoclonal Antibody

Specifically detects MSH2 Clone: FE11 in Human, Mouse samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting

The MSH2 gene is one of at least 4 genes encoding proteins involved in the repair of mismatch nucleotides following DNA replication or repair. Mutations in the MSH2 gene contribute to the development of sporadic colorectal carcinoma, while germline MSH2 mutations are responsible for ∽50% of inherited, non-polyposis colorectal carcinoma (HNPCC). MSH2 encodes a protein of 934 amino acids.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MSH2
Applications Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone FE11
Conjugate Unconjugated
Formulation In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Host Species Mouse
Immunogen a C-terminal fragment of human MSH2
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽100kDa MSH2 protein in HCT116 and SW480 cells and in colon tissue.
Target Species Human, Mouse
Content And Storage 2°C to 8°C
Form Purified
Isotype IgG1
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