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Description
The N14-47 monoclonal antibody recognizes RNA-binding protein Musashi homolog 1 (Musashi-1 or MSI1) that represses the translation of particular mRNAs by binding specific RNA sequence motifs. MSI1 contains two RNA-recognition domains at amino acids 20-110 and 109-186. It is expressed in early lineage cells, such as neural stem/progenitor cells, small intestinal stem cells, and mammary stem cells. MSI1 has also been detected in many human cancers, including gliomas, melanomas, colorectal adenomas and adenocarcinomas, suggesting its involvement in cancer development.
Specifications
Specifications
| Antigen | MSI1 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | N14-47 |
| Conjugate | PE |
| Description | Musashi-1, RNA-binding protein Musashi homolog 1, MSI1H |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human MSI1 a.a. 221-311 Recombinant Protein |
| Purification Method | Affinity Purified |
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