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Description
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq
Specifications
Specifications
| Antigen | msh homeobox 2 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 1F6 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant MSX2. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | MSX2 |
| Gene Accession No. | NM_002449 |
| Gene Alias | CRS2/FPP/HOX8/MSH/PFM/PFM1 |
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