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MUC2 Mouse anti-Human, Unlabeled, Clone: CCP58, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555926

Catalog No. BDB555926


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Description

Description

Reacts with the core peptide of the MUC2 protein, a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200kDa) and an amino acid composition rich in serine, threonin, proline and glycine. The core protein contains a domain of 23 amino-acid tandem repeats which function as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This antibody has been shown to be relatively tissue specific, being associated predominantly with intestinal tissue and is highly reactive with colon and gastric tumors. The antibody is suitable for staining formalin-fixed, paraffin-embedded tissue sections following citrate pretreatment.

Host Species: Mouse
Clone: CCP58
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

TRUSTED_SUSTAINABILITY
Specifications

Specifications

MUC2
Monoclonal
0.5mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Affinity Purified
RUO
Primary
Store undiluted at 4°C
Immunohistochemistry
CCP58
Unconjugated
Mouse
0.1 mg
Cell Biology
Human
IgG1 κ
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