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MBNL1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA110038

Catalog No. 01-670-295

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Several important human diseases are associated with expansion of polynucleotide sequences, in most cases trinucleotide repeats. Myotonic dystrophy (DM1) is one of these diseases, and is associated with increases in the number of CTG repeats in the 3' UTR of the gene encoding myotonin (a.k.a. DM Kinase, DMK or myotonin-Protein Kinase), a ser/thr kinase expressed specifically in muscle. Mammalian genomes contain three muscleblind-like proteins, generally referred to as MBNL1, MBNL2 and MBNL3, and all three were found to associate with long double stranded CUG RNA repeats, thus, being triplet repeat expansion dsRNA-binding proteins.

Specifications

Specifications

MBNL1
Monoclonal
Assay dependent
MBNL1
Liquid
MBNL1
Recombinant human Muscleblind protein
500μL
Store at -20°C
Primary
282635, 4154, 56758
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Unconjugated
tissue culture supernatant with 10mM sodium azide
Q9NR56, Q9JKP5
Muscleblind-like protein 1, MBNL
Murine
IgG1, κ
RUO
Antibody
Monoclonal
Human, Murine, Rat
Documents
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