Invitrogen™ Mycobacterium tuberculosis Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA17231

Catalog No. PA17231

Description

PA1-7231 detects the Mycobacterium tuberculosis. PA1-7231 has been successfully used in immunohistochemistry procedures. The PA1-7231 immunogen is tuberculosis PPD (purified protein derivative). Store at 4ºC for up to 6 months. For longer storage, store at -20ºC, Avoiding freeze/thaw cycles.

Tuberculosis is a chronic bacterial infection which remains one of the leading killers of young adults world wide. Mycobacterium tuberculosis enters the alveoli by airborne transmission. They are engulfed by alveolar macrophages but resist destruction. Although the exact mechanism is not known, it is suspected that that Mycrobacterium tuberculosis survives by preventing the fusion of the phagosome and lysosome. As the bacterium accumulates it forms a tubercle, spreads to the lymph nodes and becomes a systemic infection. Although treatments for tuberculosis do exist, new strains of Mycobacterium tuberculosis that appear to have multiple-drug resistance (MDR) pose a considerable threat to public health.

Specifications

• Antigen: Mycobacterium tuberculosis
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: m tuberculosis; M. tuberculosis
• Immunogen: Purified PPD.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry
• Concentration: 5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG