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Description
Reacts with myeloperoxidase (MPO), a hemoprotein of 140kDa, composed of two heavy subunits of 52kDa and two light chains of 15kDa. MPO is stored in primary azurophilic granules of neutrophils and plays a major role in the bactericidal activity of neutrophils during phagocytosis. It catalyzes the generation of hypochlorous acid, a powerful oxidant. 1B10 antibody detects MPO in neutrophils, monocytes and HL-60 cells. This reagent is suitable for immunohistochemical staining of acetone-fixed, frozen tissue section and/or formalin-fixed,
paraffin-embedded tissue sections with TUF pretreatment.
Host Species: Mouse
Clone: 1B10
Isotype: IgG1 κ
Species Reactivity: Human
Immunohistochemistry, Immunohistochemistry (Frozen), Intracellular Staining
Specifications
Specifications
| Antigen | Myeloperoxidase |
| Applications | Immunohistochemistry |
| Classification | Monoclonal |
| Clone | 1B10 |
| Concentration | 0.5mg/mL |
| Conjugate | Unconjugated |
| Description | MPO |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
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For Research Use Only.
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