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MYOC, Mouse, Clone: 2B4, Abnova™

Catalog No. 89123235 Shop All Abnova Corporation Products
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89-123-235 100 μg
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Catalog No. 89-123-235 Supplier Abnova Corporation Supplier No. H00004653M02
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Description

Mouse monoclonal antibody raised against a full-length recombinant MYOC.

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq

Sequence: MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM

Specifications

Antigen MYOC
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2B4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full-length recombinant MYOC.
Formulation PBS with no preservative; pH 7.4
Gene MYOC
Gene Accession No. BC029261
Gene Alias GLC1A/GPOA/JOAG/JOAG1/TIGR/myocilin
Gene Symbols MYOC
Host Species Mouse
Immunogen MYOC (AAH29261, 1 a.a. ∼ 504 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4653
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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