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Description
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq
Specifications
Specifications
| Antigen | NAGLU |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 1B7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant NAGLU. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | NAGLU |
| Gene Accession No. | NM_000263 |
| Gene Alias | MPS-IIIB/MPS3B/NAG/UFHSD |
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