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Nanog Mouse anti-Mouse, Alexa Fluor 647, Clone: M55-312, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 560279

Catalog No. BDB560279


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Description

Description

The M55-312 monoclonal antibody reacts with mouse Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.

Host Species: Mouse
Clone: M55-312
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Mouse Nanog Recombinant Protein

Bioimaging, Intracellular Staining

Specifications

Specifications

Nanog
M55-312
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Mouse
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
Alexa Fluor 647
Affinity Purified
Mouse Nanog Recombinant Protein
50 Tests
Cell Biology
Primary
Murine
SDS
Documents
Product Certifications
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