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Nanog Mouse anti-Mouse, PE, Clone: M55-312, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560277

Catalog No. BDB560277


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Description

Description

The M55-312 monoclonal antibody reacts with mouse Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.

Host Species: Mouse
Clone: M55-312
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Mouse Nanog Recombinant Protein

Intracellular Staining

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Nanog
Monoclonal
PE
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
M55-312
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Mouse Nanog Recombinant Protein
50 Tests
Cell Biology
Mouse
IgG1 κ
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