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Nanog Mouse anti-Mouse, PE, Clone: M55-312, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 560277
Description
The M55-312 monoclonal antibody reacts with mouse Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
Host Species: Mouse
Clone: M55-312
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Mouse Nanog Recombinant Protein
Intracellular Staining

Specifications
Nanog | |
Monoclonal | |
PE | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
M55-312 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Mouse Nanog Recombinant Protein | |
50 Tests | |
Cell Biology | |
Mouse | |
IgG1 κ |
Safety and Handling
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