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Description
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq
Specifications
Specifications
| Antigen | NDUFS4 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3F11 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant NDUFS4. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | NDUFS4 |
| Gene Accession No. | NM_002495 |
| Gene Alias | AQDQ |
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