MilliporeSigma™ anti-Nerve Growth Factor Receptor, p75 ; Polyclonal; ™ (Chemicon™)

Supplier:  MilliporeSigma™ AB1554/DEL

Catalog No. 50-173-126

Description

There are two classes of neurotrophin cell-surface receptors. The p75 receptor (also known as the low-affinity neurotrophin receptor, LANR) is common to all members of the neurotrophin family( which includes nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4 (NT-4). The NGF receptor (p75) is belongs to the tumor necrosis factor receptor family and binds all four neurotrophins. The roles of p75 are under investigation but may be involved in regulating the response to the neurotrophins and increasing the affinity of high-affinity Trk receptors (which also bind the four neurotrophins).

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting

Specifications

• Antigen: Nerve Growth Factor Receptor (p75)
• Conjugate: Unconjugated
• Immunogen: Extracellular fragment generated from sequences from the third exon of mouse p75 (amino acids 43-161).
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Serum

• Classification: Polyclonal
• Host Species: Rabbit
• Quantity: 100 μL
• Research Discipline: Neuroscience
• Target Species: Chicken, Human, Mouse, Rat