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neurofascin homolog (chicken), Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89004555 Shop All Abnova Corporation Products
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89-004-555 50 μL
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Catalog No. 89-004-555 Supplier Abnova Corporation Supplier No. H00023114A01
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Mouse polyclonal antibody raised against a partial recombinant NFASC.

This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined

Sequence: KDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNS

Specifications

Antigen neurofascin homolog (chicken)
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant NFASC.
Formulation 50% glycerol
Gene NFASC
Gene Accession No. NM_001005388
Gene Alias DKFZp686P2250/FLJ46866/KIAA0756/NF/NRCAML
Gene Symbols NFASC
Host Species Mouse
Immunogen NFASC (NP_001005388, 661 a.a. ∼ 758 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Research Discipline Cell Adhesion
Whole Molecule Yes
Primary or Secondary Primary
Gene ID (Entrez) 23114
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Serum
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