Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

NFAT-1 Mouse, Unlabeled, Clone: 1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 610702

 View more versions of this product

Catalog No. BDB610702


Only null left
Add to Cart

Description

Description

T cells are activated and induced to proliferate following binding of their respective antigen. The process of includes expression of genes that encode factors (i.e., cytokines) which regulate various cell types. Modulation of gene expression is conducted by an array of specific interactions between transcription factors and DNA. NFAT-1 (Nuclear Factor of Activated T cells) is a transcription factor that regulates expression of the interleukin-2 gene. Thus, NFAT-1 DNA binding activity is undetectable in resting cells, but increases during T-cell activation. NFAT-1, a protein of 921 amino acids, is part of an oligomeric transcription factor that also contains Fra-1 and JunB. NFAT-1 was initially described as a phosphoprotein and is dephosphorylated in activated T cells transformed with the leukemia virus HTLV-l.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NFAT-1
Monoclonal
250μg/mL
NF-ATc2; NFATP; KIAA0611
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
1
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50 μg
Cell Biology
Canine, Human
IgG1
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.

For Research Use Only.