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NFKB1 (A01), Mouse anti-Human, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a partial recombinant NFKB1.

Manufacturer:  Abnova Corporation H00004790A01

Catalog No. 89-003-045


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Description

Description

This gene encodes a 105kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50kDa protein. The 105kDa protein is a Rel protein-specific transcription inhibitor and the 50kDa protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: MDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI
Specifications

Specifications

NFKB1
Unconjugated
50% glycerol
BC051765
DKFZp686C01211|EBP-1|KBF1|MGC54151|NF-kappa-B|NFKB-p105|NFKB-p50|p105|p50
Mouse
50 uL
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human
ELISA, Western Blot
Mouse polyclonal antibody raised against a partial recombinant NFKB1.
NFKB1
Liquid
NFKB1
NFKB1 (AAH51765, 860 a.a. ~ 969 a.a) partial recombinant protein with GST tag.
RUO
Primary
4790
Documents
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