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NKB1 Mouse anti-Human, Unlabeled, Clone: DX9, BD

Catalog No. BDB555964 Shop All BD Biosciences Products
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BDB555964 0.1 mg
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Catalog No. BDB555964 Supplier BD Biosciences Supplier No. 555964
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Description

Mouse Monoclonal Antibody

Reacts with the killer cell inhibitory receptor (KIR), NKB1, a 70kDa glycoprotein, member of the Ig superfamily, expressed on a subset of natural killer cells and a small subset of T cells. Expression of NKB1 has been observed to vary among individuals. KIR molecules specifically recognize a certain group of HLA class I antigens. Interaction of NKB1 with specific HLA-B antigen on a target cell inhibits cell mediated cytotxicity, possibly by delivering a negative signal preventing lymphocyte activation. It is suggested that this MHC class I-KIR interaction works as a regulatory mechanism of NK and T-cell responses to antigenic challenge. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: DX6
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen NKB1
Applications Flow Cytometry
Classification Monoclonal
Clone DX9
Concentration 0.5mg/mL
Conjugate Unconjugated
Description KIR3DL1; CD158E; CD158E1; KIR antigen 3DL1; KIR; KI3L1; NKAT-3; NKB1; NKB1B
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human NK Cell Clone
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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