NKB1 Mouse anti-Human, FITC, Clone: DX9, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 340483

Catalog No. BDB340483

Description

Anti-human killer inhibitory receptor (KIR), NKB1, (Anti-Hu KIR [NKB1]) recognizes a 70kDa glycoprotein that is a member of the p58/NK-associated transcript (NKAT) family of class I receptors. KIR (NKB1) is an MHC class I receptor that inhibits NK celln++ated cytotoxicity on target cells that express HLA-B molecules of the Bw4 serotype, but it does not affect recognition of HLA-A or HLA-C antigens. KIR (NKB1)-mediated inhibition is abrogated by binding of Anti-Hu KIR (NKB1). Anti-Hu KIR (NKB1) also regulates T-cell activation initiated through the T-cell antigen receptor (TCR) complex. KIR (NKB1) is expressed on a subset of human NK cells (CD3-/CD56+), NK cell clones, and a subset of human T lymphocytes.

Flow Cytometry

Specifications

• Antigen: NKB1
• Classification: Monoclonal
• Concentration: 1.6μg/mL
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Immunogen: Human NK Cell Clone
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

• Applications: Flow Cytometry
• Clone: DX9
• Conjugate: FITC
• Host Species: Mouse
• Quantity: 50 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.