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NKp46 Mouse anti-Human, Unlabeled, Clone: 9E2/NKP46, BD

Mouse Monoclonal Antibody

$164.70 - $560.00

Specifications

Antigen NKp46
Clone 9E2/NKP46
Applications Flow Cytometry
Classification Monoclonal
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB557911
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BD Biosciences
557911
0.1 mg
Each for $164.70
Only null left
Add to Cart
 
BDB557847
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BD Biosciences
557847
0.5 mg
Each for $560.00
Only null left
Add to Cart
 
Description

Description

NKp46, a major cytoxicity receptor of NK cells, is a type I membrane glycoprotein (46kDaa) is expressed on resting and activated NK cells. Its extracellular region contains two C2-type, Ig-like domains. The transmembrane domain contains a positively charged amino acid (Arg) which could be involved in stabilizing the association with CD3ζ. Its intracellular region does not contain immunoreceptor tyrosine-based activating motifs (ITAM), but it is linked to intracytoplasmic transduction machinery by its association with CD3ζ and FcεRIγ adaptor proteins. NKp46 along with NKp30 and NKp44 are referred to as natural cytoxicity receptors (NCR) and play a very important role in killing virus-infected, tumor cells and MHC-class I-unprotected cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: 9E2
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Specifications

Specifications

NKp46
Flow Cytometry
Unconjugated
RUO
Human
IgG1 κ
Affinity Purified
9E2/NKP46
Monoclonal
Mouse
Immunology
Human NKp46 Recombinant Protein
Primary
Store undiluted at 4°C
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