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Description
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq
Specifications
Specifications
| Antigen | N-myc (and STAT) interactor |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 9B8 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant NMI. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | NMI |
| Gene Accession No. | BC001268 |
| Gene Symbols | NMI |
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