NQO1, Mouse, Clone: 1E3-A6, Abnova™

Catalog No.	Quantity
89-021-299	100 μg

Catalog No. 89-021-299 Supplier Abnova Corporation Supplier No. H00001728M01

Description

Mouse monoclonal antibody raised against a full-length recombinant NQO1.

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Sequence: MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK

Specifications

• Antigen: NQO1
• Applications: ELISA, Immunofluorescence, Immunoprecipitation, KnockDown, Western Blot
• Classification: Monoclonal
• Clone: 1E3-A6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant NQO1.
• Formulation: PBS with no preservative; pH 7.4
• Gene: NQO1
• Gene Accession No.: BC007659
• Gene Alias: DHQU/DIA4/DTD/NMOR1/NMORI/QR1
• Gene Symbols: NQO1
• Host Species: Mouse
• Immunogen: NQO1 (AAH07659, 1 a.a. ∼ 274 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1728
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ