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NAD(P)H dehydrogenase, quinone 1, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against a full-length human NQO1 protein.

Supplier:  Abnova Corporation H00001728D01P

Catalog No. 89-017-563


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Description

Description

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Sequence: MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Specifications

Specifications

NAD(P)H dehydrogenase, quinone 1
Polyclonal
Rabbit polyclonal antibody raised against a full-length human NQO1 protein.
NQO1
DHQU/DIA4/DTD/NMOR1/NMORI/QR1
Rabbit
Affinity Purified
RUO
1728
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
Western Blot
Unconjugated
PBS with no preservative; pH 7.4
NM_000903.2
NQO1
NQO1 (NP_000894.1, 1 a.a. ∼ 274 a.a) full-length human protein.
100 μg
Primary
Human, Mouse
Antibody
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