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NRG1, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Catalog No. 89002943 Shop All Abnova Corporation Products
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89-002-943 100 μg
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Catalog No. 89-002-943 Supplier Abnova Corporation Supplier No. H00003084D01P
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Rabbit polyclonal antibody raised against a full-length human NRG1 protein.

The protein encoded by this gene was originally identified as a 44kDa glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq

Sequence: MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPQLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTPFLSLPE

Specifications

Antigen NRG1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against a full-length human NRG1 protein.
Formulation PBS with no preservative; pH 7.4
Gene NRG1
Gene Accession No. NM_013958.1
Gene Alias ARIA/GGF/GGF2/HGL/HRG/HRG1/HRGA/NDF/SMDF
Gene Symbols NRG1
Host Species Rabbit
Immunogen NRG1 (NP_039252.1, 1 a.a. ∼ 241 a.a) full-length human protein.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3084
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Purified
Isotype IgG
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