NUP107 Mouse anti-Bovine, Chicken, Drosophila, Equine, Human, Mouse, Porcine, Rat, Yeast, Clone: 39C7, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA110031
For immunofluorescence on yeast cells, try MCA-39C7 diluted 1:100 to 1:500. For immunofluorescence on mammalian cells try at 1:50 to 1:100.The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.
|Yeast nuclear preparation.|
|Store at 4°C short term. For long term storage, Store at -20°C, avoiding freeze/thaw cycles.|
|100059287, 100516909, 101751988, 103468, 116555, 34481, 504823, 57122|
|tissue culture supernatant with no preservative|
|P52590, P57740, Q8BH74, Q9V466|
|Bovine, Chicken, Drosophila, Equine, Human, Mouse, Porcine, Rat, Yeast|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok