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NXF1, Rabbit, Monoclonal Antibody, Abnova™

Catalog No. 89201620 Shop All Abnova Corporation Products
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1 mg x up to 3 Abs
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Catalog No. Quantity
89-201-620 1 mg x up to 3 Abs
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Catalog No. 89-201-620 Supplier Abnova Corporation Supplier No. H00010482K

Description

Includes

Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Rabbit monoclonal antibody raised against a human NXF1 peptide using ARM Technology.

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Antigen NXF1
Applications ELISA, Western Blot
Classification Monoclonal
Concentration 1mg
Conjugate Unconjugated
Description nuclear RNA export factor 1
Formulation In 1X PBS, pH 7.4
Gene NXF1
Gene Accession No. NXF1
Gene Alias DKFZp667O0311, MEX67, TAP
Gene Symbols NXF1
Host Species Rabbit
Immunogen A synthetic peptide of human NXF1
Quantity 1 mg x up to 3 Abs
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10482
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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