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2',5'-oligoadenylate synthetase 1, 40/46kDa, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Shop All Abnova Corporation ProductsDescription
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
Specifications
Specifications
| Antigen | 2',5'-oligoadenylate synthetase 1, 40/46kDa |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against a full-length human OAS1 protein. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | OAS1 |
| Gene Accession No. | NM_016816.2 |
| Gene Alias | IFI-4/OIAS/OIASI |
| Gene Symbols | OAS1 |
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