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OPTN, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human OPTN peptide using ARM Technology.

Supplier:  Abnova Corporation H00010133K

Catalog No. 89-209-845


Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Description

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Specifications

OPTN
Monoclonal
Unconjugated
In 1X PBS, pH 7.4
OPTN
OPTN
A synthetic peptide of human OPTN
RUO
10133
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
ELISA, Western Blot
1mg
optineurin
OPTN
FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
Rabbit
1 mg x up to 3 Abs
Primary
Human
Liquid
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