Invitrogen™ DDOST Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527644

Catalog No. PIPA527644

Description

Recommended positive controls: A431, H1299, HeLa, HepG2. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (86%), Xenopus laevis (90%), Dog (97%), Pig (94%), Chicken (93%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation end products (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

Specifications

• Antigen: DDOST
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDOST
• Gene Alias: advanced glycation endproduct receptor 1; advanced glycation end-product receptor 1; AGER1; AGE-R1; CDG1R; Ddost; DDOST 48 kDa subunit; dolichyl-diphosphooligosaccharide protein glycosyltransferase; dolichyl-diphosphooligosaccharide-protein glycosyltransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); dolichyl-di-phosphooligosaccharide-protein glycotransferase; dolichyl-diphosphooligosaccharide-protein glycotransferase; KIAA0115; MGC2191; OK/SW-cl.45; OKSWcl45; oligosaccharyl transferase 48 kDa subunit; oligosaccharyltransferase 48 kDa subunit; oligosaccharyltransferase OST48; oligosaccharyltransferase subunit 48; OST; OST48; WBP1; wu:fa11d01; zgc:66068; zgc:66068 protein; zgc:77478
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1650
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.94 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P39656
• Gene Symbols: DDOST
• Immunogen: Recombinant protein encompassing a sequence within the center region of human OST48. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov