OTUB1, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human OTUB1 peptide using ARM Technology.

Supplier:  Abnova Corporation H00055611K

Catalog No. 89-210-617

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: OTUB1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: OTUB1
• Gene Symbols: OTUB1
• Immunogen: A synthetic peptide of human OTUB1
• Regulatory Status: RUO
• Gene ID (Entrez): 55611
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: OTU domain, ubiquitin aldehyde binding 1
• Gene: OTUB1
• Gene Alias: FLJ20113, FLJ40710, HSPC263, MGC111158, MGC4584, OTB1, OTU1
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid