Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. BDB559957

OX-40 Ligand Mouse anti-Rat, Unlabeled, Clone: ATM-2, BD

Catalog No. BDB559957 Shop All BD Biosciences Products
Change view
Click to view available options
Quantity:
0.5 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
BDB559957 0.5 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. BDB559957 Supplier BD Biosciences Supplier No. 559957

Description

Mouse Monoclonal Antibody

The ATM-2 antibody reacts with rat CD252 (OX-40 Ligand, OX-40L), a member of the TNF Ligand superfamily. Although there is controversy regarding mouse OX-40L expression, OX-40L has been shown to be expressed on human dendritic cells and mouse activated B lymphocytes. Rat OX-40L interacts with OX-40 Antigen (CD134) found predominantly on activated T cells. The OX-40L-OX-40 interaction is reciprocally costimulatory in that both T cells and B cells are activated in cross-linking. Rat OX-40L mRNA has been detected in various HTLV-I-transformed T-cell lines: F344-S1, WKA-S1, and ACI-S1. In addition, total rat spleen cells activated with 5 ng/ml PMA and 0.5 µg/ml ionomycin for two days showed OX-40L expression, as determined by flow cytometric analysis, with the ATM-2 mAb. As observed in the mouse and human systems, rat OX-40L also costimulates IL-2 production and proliferation of anti- D3-activated rat T cells. The ATM-2 mAb blocks the costimulatory activity of OX-40L on rat T- cell proliferation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen OX-40 Ligand
Applications Flow Cytometry
Classification Monoclonal
Clone ATM-2
Concentration 0.5mg/mL
Conjugate Unconjugated
Description OX-40L, OX-40 Ligand
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen ACI-S1 rat T-cell lymphoma cell line
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.