P-glycoprotein Mouse anti-Human, PE, Clone: 15D3, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 340555

Catalog No. BDB340555

Description

Anti-P-glycoprotein (P-gp) recognizes a 170kDa protein from multidrug-resistant (MDR) cells.P-glycoprotein is a transmembrane protein that acts as an ATP-dependent efflux pump for a large variety of drugs. This efflux activity has been suggested to lead to resistance to the drugs used in chemotherapy. P-glycoprotein is present in many normal cell types including secretory cells, and might protect them from naturally occurring xenobiotics.

Applications:

Flow Cytometry

Specifications

• Antigen: P-glycoprotein
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Immunogen: BA3T3 fibroblast line (BATV.2) transfected with the human MDR1 gene
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

• Applications: Flow Cytometry
• Clone: 15D3
• Description: CD243
• Host Species: Mouse
• Quantity: 50 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.